Adipose-Derived Stem Cell Delivery into Collagen Gels Using Chitosan Microspheres

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Adipose-derived stem cell delivery into collagen gels using chitosan microspheres.

Integration of stem cells to injured tissues requires an appropriate delivery device and scaffolding system. In the present study we have developed an in vitro strategy to load and release adipose-derived mesenchymal stem cells (ASC) from chitosan microspheres (CSM) into a collagen gel scaffold. Porous CSM of uniform size and composition were prepared and used as a stem cell carrier. ASC were a...

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Constructing a collagen hydrogel for the delivery of stem cell-loaded chitosan microspheres.

Multipotent stem cells have been shown to be extremely useful in the field of regenerative medicine. However, in order to use these cells effectively for tissue regeneration, a number of variables must be taken into account. These variables include: the total volume and surface area of the implantation site, the mechanical properties of the tissue and the tissue microenvironment, which includes...

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Differentiation of Adipose-derived Stem Cells into Schwann Cell Phenotype in Comparison with Bone Marrow Stem Cells

Objective(s) Bone marrow is the traditional source of human multipotent mesenchymal stem cells (MSCs), but adipose tissue appears to be an alternative and more readily available source. In this study, rat adipose-derived stem cells (ADSCs) were induced to differentiate into Schwann-like cells and compared with rat bone marrow stem cells (BMSCs) for their Schwann-like cells differentiation pote...

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ژورنال

عنوان ژورنال: Tissue Engineering Part A

سال: 2010

ISSN: 1937-3341,1937-335X

DOI: 10.1089/ten.tea.2009.0404